Stephy Publishers

  Correlation of Erythrocyte Distribution Width Values with Preeclampsia and Preeclampsia with Severity Criteria Aim: To determine the correlation of the red cell distribution width values with pre-eclampsia and pre-eclampsia with severity criteria. Materials and methods: Cross-sectional, prospective study of patients who met the inclusion criteria in the period from August 2019 to August 2020. Statistical analysis was performed using Student's t test and Spearman's correlation to calculate the dependence between the non-parametric variables, the value of p<0.05 was considered statistically significant. Results: 9 patients with pre-eclampsia and 30 pre-eclampsia were obtained with severity criteria. There was no statistical difference when comparing the RDW of patients with pre-eclampsia and pre-eclampsia with severity criteria (p=0.226), in patients with systolic blood pressure values ≥160mmHg there was an increase in RDW levels (p=0.042) Objective: To determine the correla...

 m R.N.A. Purifications Process: Affinity Chromato-Graphy, Magnetic Beads and Graphene Coated Large Scale Production and Toxicological Aspects Aim of this work is to verify the state of the art related m R.N.A. purification process , the technology used as well as the materials employed. New methods vs classic methods: the use of affinity cromato-graphy or and high‐gradient magnetic separation (H.G.M.S.). In particular the use of magnetic beads since introduction of the graphene coated ones. Various producers provide many kind of magnetic beads with various grade of efficiency in separation. Becasue today there is a great debate around graphene derivates peresence (or not) in vials of m R.N.A. VACCINE it is relevant to better clarify the production process as well and the materials used. During last periods in order to fight Covid-19 pandemia was introduced with emergency autorization a new class of vaccine: The m R.N.A. vaccine. This innovative biopharmaceutical products was devel...