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Showing posts with the label Endocrinology Care

Diabetic Emergencies: Experience of a Tertiary Endocrine Center | Stephy Publishers

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  SOJ Diabetes and Endocrinology Care - (SOJDEC) |  Stephy Publishers Abstract Purpose:  In this study, we aimed to retrospectively evaluate the demographic data, clinical features, laboratory data, precipitating causes of diabetic emergencies, complications in the follow-up of adult patients who applied to our hospital due to diabetic emergencies. Methods:  The study included patients aged 18 years and older referred to a tertiary endocrine center with diabetic ketoacidosis (DKA), hyperosmolar hyperglycemic state (HHS) hypoglycemia between January 2010 and May 2018. Results:  The study was carried out with 165patients, 69(41.8%) males, and 96(58.2%) females. The mean age of the patients was 43.8±20.4(18- 88). Of these patients, 77% (n=127) had DKA, 17% (n=28) had HHS and 6% (n=10) had hypoglycemia. Of the patients 55.2% (n=91) were type 1 DM, 44.8% (n=74) were type 2DM. When the precipitating causes of diabetic emergencies were examined, 32.7%(n=54) poor ...

Bone Turnover Markers and Adipocytokinesresponse to Weight Reduction among Obese Patients with Type 2 Diabetes Mellitus| Stephy Publishers

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SOJ Diabetes and Endocrinology Care - (SOJDEC) | Stephy Publishers   Abstract Background: Type 2 diabetes mellitus (T2DM) is a highly prevalent disease associated with increased the risk of fracture due to altered bone micro architecture and/or poor quality as key factors. Bone remodeling appears to be impaired among patients with T2DM as both markers of bone formation and markers of bone resorption are decreased when compared to healthy subjects. Objective: This study aimed to detect if weight reduction modulates adipokines and markers of bone turnover among T2DM patients. Material and Methods: Eighty obese patients with T2DM (46 men and 34 women), their age ranged from 40-53 years and their body mass index ranged from 30-36 kg/m2 were equally assigned into 2 groups: the weight reduction group received aerobic exercises, diet regimen, where the control group received medical treatment only for 6 months. Results: The mean values of body mass index (BMI), leptin, resistin, visfatin ...

Management of Labor and Psychiatricpostpartum Diseases Using Potential Anti-obesity and Antidiabetic Plants in Cameroon| Stephy Publishers

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  SOJ Diabetes and Endocrinology Care - (SOJDEC) | Stephy Publishers Abstract Globally more than 550 women die per year from childbirth-related causes. Around 9% of women suffer from postpartum post-traumatic stress disorder after childbirth. Postpartum bipolar disorder is humor episodes such as mania, hypomania or depression, which start throughout pregnancy or in few weeks after child bearing. Fifty percent (50%) worldwide estimation of motherly deaths arise in sub-Saharan Africa region alone. Depression is a devastating temperament and mental sickness touching around 13% of postpartum mothers worldwide. The occurrence of 25%-60% of depression is typical of low- and middle-income countries. A combined prevalence of 14.4% of teenage deliveries was revealed in Cameroon where there is unsatisfactory information on the risk factors of motherly mortality and mother care after childbirth. In hinterland local therapists especially in Bororo and Pygmies communities, have developed indige...

Metabolic Risk Markers in Insulin Resistance and Non-Insulin Resistance Type 2 Diabetes Mellitus| Stephy Publishers

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  SOJ Diabetes and Endocrinology Care - (SOJDEC)| Stephy Publishers Abstract Aim: Type 2 diabetes mellitus (T2DM) is the most common metabolic disorder and its pathogenesis is characterized by a combination of peripheral insulin resistance and impaired insulin secretary capacity of pancreatic β cell. Over the years, there has been increasing deaths from T2DM. In Myanmar, there is little information on its causes, due to few published data on the prevalence of MS and its association with T2DM. This study aims at identifying the metabolic risk markers leading to MS in T2DM, as well as the impact of MS on the insulin resistance. Methods: Hundred T2DM patients were recruited from Diabetic Clinic, Yangon General Hospital. The clinical evaluation consisted of waist circumference, blood pressure, height and weight measurements; the biochemical analysis included determination of fasting plasma glucose, serum insulin and fasting lipid profile. Plasma glucose level was determined by the glu...

Resolution of Severe Anorexia Nervosa Associated with Gender Dysphoria (Dysphorexia) by Testosterone Therapy| Stephy Publishers

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  SOJ Diabetes and Endocrinology Care - (SOJDEC) | Stephy Publishers Abstract Anorexia nervosa is a severe and potentially lethal eating disorder. In transgender youth with severe gender dysphoria, a severe eating disorder (proposed name: dysphorexia), coherent with anorexia nervosa may be triggered by the desire to avoid the cisgender pubertal transition. In these patients, gender-affirming hormone therapy can be extremely effective. We report hereby the cases of two female-to-male transsexual patients with severe gender dysphoria whose anorexia nervosa was related to their pubertal development and who promptly recovered when they started gender-affirming hormone therapy with testosterone, after very limited success with standard psychotherapy and pharmacotherapy for anorexia nervosa. Our patients could not access pubertal suppression due to lack of parental consent in one case and failure to express the conflict in the other. We postulate that avoiding the cisgender pubertal t...