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Bone Turnover Markers and Adipocytokinesresponse to Weight Reduction among Obese Patients with Type 2 Diabetes Mellitus| Stephy Publishers

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SOJ Diabetes and Endocrinology Care - (SOJDEC) | Stephy Publishers   Abstract Background: Type 2 diabetes mellitus (T2DM) is a highly prevalent disease associated with increased the risk of fracture due to altered bone micro architecture and/or poor quality as key factors. Bone remodeling appears to be impaired among patients with T2DM as both markers of bone formation and markers of bone resorption are decreased when compared to healthy subjects. Objective: This study aimed to detect if weight reduction modulates adipokines and markers of bone turnover among T2DM patients. Material and Methods: Eighty obese patients with T2DM (46 men and 34 women), their age ranged from 40-53 years and their body mass index ranged from 30-36 kg/m2 were equally assigned into 2 groups: the weight reduction group received aerobic exercises, diet regimen, where the control group received medical treatment only for 6 months. Results: The mean values of body mass index (BMI), leptin, resistin, visfatin ...

Metabolic Risk Markers in Insulin Resistance and Non-Insulin Resistance Type 2 Diabetes Mellitus| Stephy Publishers

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  SOJ Diabetes and Endocrinology Care - (SOJDEC) |  Stephy Publishers Abstract Aim:  Type 2 diabetes mellitus (T2DM) is the most common metabolic disorder and its pathogenesis is characterized by a combination of peripheral insulin resistance and impaired insulin secretary capacity of pancreatic β cell. Over the years, there has been increasing deaths from T2DM. In Myanmar, there is little information on its causes, due to few published data on the prevalence of MS and its association with T2DM. This study aims at identifying the metabolic risk markers leading to MS in T2DM, as well as the impact of MS on the insulin resistance. Methods:  Hundred T2DM patients were recruited from Diabetic Clinic, Yangon General Hospital. The clinical evaluation consisted of waist circumference, blood pressure, height and weight measurements; the biochemical analysis included determination of fasting plasma glucose, serum insulin and fasting lipid profile. Plasma glucose level was...

Metabolic Risk Markers in Insulin Resistance and Non-Insulin Resistance Type 2 Diabetes Mellitus| Stephy Publishers

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  SOJ Diabetes and Endocrinology Care - (SOJDEC)| Stephy Publishers Abstract Aim: Type 2 diabetes mellitus (T2DM) is the most common metabolic disorder and its pathogenesis is characterized by a combination of peripheral insulin resistance and impaired insulin secretary capacity of pancreatic β cell. Over the years, there has been increasing deaths from T2DM. In Myanmar, there is little information on its causes, due to few published data on the prevalence of MS and its association with T2DM. This study aims at identifying the metabolic risk markers leading to MS in T2DM, as well as the impact of MS on the insulin resistance. Methods: Hundred T2DM patients were recruited from Diabetic Clinic, Yangon General Hospital. The clinical evaluation consisted of waist circumference, blood pressure, height and weight measurements; the biochemical analysis included determination of fasting plasma glucose, serum insulin and fasting lipid profile. Plasma glucose level was determined by the glu...