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 The Role of Mutations on Genes KRT3 & KRT12 in Meesmann Corneal Dystrophy Syndrome Meesmann corneal dystrophy syndrome is a genetic disorder of the eye that affects the cornea. This condition is characterized by the formation of small round cysts in all parts of the corneal layer, called the corneal epithelium. Meesmann corneal dystrophy syndrome is caused by a mutation in the KRT12 gene, which is located in the long arm of chromosome 17 as 17q21.2, or the KRT3 gene, which is located in the long arm of chromosome 12, as 12q13.13. Meesmann corneal dystrophy syndrome is a genetic disorder of the eye that affects the cornea. This condition is characterized by the formation of small round cysts in all parts of the corneal layer, called the corneal epithelium. This part of the cornea acts as a barrier to prevent foreign matter such as dust and bacteria from entering the eye.In people with Meesmann corneal dystrophy, cysts may appear very early in the first year of life. They usuall...

 Neuroscience Infectious diseases take time to show clinical signs. The most common is to present a dysfunction of the target organ, that is, if the infection is in the neural system the most common sign is headache, if the infection is pulmonary the most common symptom is cough, if the infection is in gastrointestinal tract, diarrhea. However, there are more general signs such as fever, in appetence and dynamic, which are generalized manifestations that reflect that the organ system is experiencing an infection. There are complementary tests that help in the correct diagnosis of these infections. The diagnosis of gastrointestinal diseases is predominantly related to the patient's history and, to a lesser extent, to the physical examination performed by the physician. Laboratory tests and imaging studies can provide objective evidence for or against a particular disease, among those included in the differential diagnosis and determined by a competent and accurate history and physic...