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Invasive Melanoma: The Treatment-Resistant Skin Cancer with the Deadly Reputation | Stephy publishers

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  Journal of Cancer Research and Clinical Therapeutics | Stephy publishers Abstract Although melanoma accounts for less than a tenth of all skin cancers, it is responsible for three quarters of skin cancer deaths. It has a more aggressive nature, tendency to metastasise and is more resistant to anti-cancer therapies than non-melanoma skin cancer. The more common skin malignancies arise from the epidermal keratinocytes but the melanoma arises from the melanocyte, sitting on the dermo-epidermal junction. The difference is the neural crest origin of the melanocyte. Cells of neural crest origin are characterised by being heterogeneous, multipotent, mobile, having a high degree of plasticity and, in development and disease able to demonstrate epidermal to mesenchymal transition. The evolutionary deployment of the neural crest cells allowed early chordate species to transform from thin sessile filter feeders into the more mobile, active, and predatory vertebrates, demonstrating adaptatio...

International Journal of Pharmaceutical Sciences - (IJPS)| Stephy Publishers

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  International Journal of Pharmaceutical Sciences | Stephy Publishers International Journal of Pharmaceutical Sciences is an official journal of the Stephy Publishers is an Open Access peer-reviewed online journal, which publishes research articles, reviews/mini-reviews, case reports, letters and guest edited single topic issues in all important areas of pharmacology, drug mechanism of action, pharmacodynamics, pharmacokinetics and toxicology, computational biopharmaceutics, drug delivery and targeting, molecular biopharmaceutics and drug disposition, pharmacokinetics, biochemical pharmacology etc. on all aspects of experimental and clinical pharmacology. International Journal of Pharmaceutical Sciences strives with an aspiration to publish reliable source of information by delightfully welcoming your valuable original articles at      #Submission https://www.stephypublishers.com/submit-manuscript.php #Openaccessjournals https://www.stephypublishers.com #Pharmaceuti...

International Journal of Dermatology and Venereology - (IJDV) | Stephy Publishers

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  International Journal of Dermatology and Venereology - (IJDV) | Stephy Publishers International Journal of Dermatology and Venereology is an Open Access, peer reviewed journal dealing with the skin and its treatments. This journal is source for original submissions, reviews, surgeon's reports, rapid communications, editorials, case reports, clinical images and letters. It provides avenues for molecular studies to clinical investigations, laboratory and clinical studies which provide new information that will be reviewed expeditiously. It gives sound and valid information about normal and pathological processes in skin development and aging and treatment, as well as basic research into histology of dermal and dermal structures that provide clinical insights and potential treatment options. It updates the source of information on all aspects of the diagnosis and management of skin diseases . #Submission https://www.stephypublishers.com/submit-manuscript.php # Dermatology # Venere...

Journal of Pregnancy and Women's Health Care - (JPWHC)| Stephy Publishers

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  Journal of Pregnancy and Women's Health Care - (JPWHC) | Stephy Publishers Journal of Pregnancy and Women's Health Care is an open access, peer-reviewed journal focuses on the publication of research in the various aspects of fertility, pregnancy, breastfeeding, maternity care, and Child Health, providing free online access to the researchers worldwide without any subscription charges. The journal welcomes manuscripts on all the circumstantial topics related to Women’s health. JPWHC includes a wide range of fields in its discipline like Obstetrics, Gynecology, Postmenopausal Health, Mental Health, Pregnancy and Reproductive Health, Gynecology Oncology, Child Birth, Autoimmune Disorders, Psychological Disorders, Women Care, primary care, health care policy. #Sumission https://www.stephypublishers.com/submit-manuscript.php To know more about # Women'sHealthCare https://www.stephypublishers.com/pregnancy-and-health-care/ #Openaccessjournals #stephypublishers https://www.step...

Journal of Cancer Research and Clinical Therapeutics - (JCRCT) | Stephy Publishers

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  Journal of Cancer Research and Clinical Therapeutics - (JCRCT) | Stephy Publishers Journal of Cancer Research andClinical Therapeutics is an open access peer reviewed and scholarly journal is dedicated to publish articles in all areas of cancer research and oncology The research provides pre-eminent papers on all areas of advanced research carried in its field. The Journal focuses on cellular, molecular, clinical and genetic studies related to diseases. The mission of our Journal is to equip with overall and authentic information on current developments in the form of review articles, case reports, brief communications etc., to cancer research. Journal of Cancer Research and Clinical therapeutics strives with an aspiration to publish reliable source of information by delightfully welcoming your valuable original articles at #Manuscriptsubmission https://www.stephypublishers.com/submit-manuscript.php #Cancerresearch https://www.stephypublishers.com/cancer-research-and-clinica...