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Showing posts with the label Cardiac myoxomata

Malignancy in a Family with Carney’s Complex| Stephy Publishers

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  Clinical Diabetes and Endocrinology - (JCDE)| Stephy Publishers Abstract Carney Complex is a genetic disease characterized by skin lentigenes and freckling and the growth of benign tumors in endocrine glands as well as cardiac myxoma. Malignant tumors in Carney’s Complex are extremely rare with few other case reports. We report the rare occurrence of ovarian malignancy and thyroid carcinoma separately in 2 out of 3 family members diagnosed with Carney Complex. Keywords Carney Complex, Cardiac myoxomata, Eendocrine tumors, Chemotherapy, Malignant tumor Learning Points a) The importance of thoroughly screening all lesions in Carney’s Complex rather than dismissing them as benign, as there is still a possibility for the lesion to be malignant. b) Malignant tumors in Carney’s complex can arise from any organ, which in the index case presented with multiple tumors over many years culminating in an ovarian malignant tumor, whereas the sister developed a thyroid malignancy. c) Acromegal...

Malignancy in a Family with Carney’s Complex| Stephy Publishers

Image
  Journal of Clinical Diabetes and Endocrinology | Stephy Publishers Abstract Carney Complex is a genetic disease characterized by skin lentigenes and freckling and the growth of benign tumors in endocrine glands as well as cardiac myxoma. Malignant tumors in Carney’s Complex are extremely rare with few other case reports. We report the rare occurrence of ovarian malignancy and thyroid carcinoma separately in 2 out of 3 family members diagnosed with Carney Complex. Keywords: Carney Complex, Cardiac myoxomata, Eendocrine tumors, Chemotherapy, Malignant tumor Learning Points a) The importance of thoroughly screening all lesions in Carney’s Complex rather than dismissing them as benign, as there is still a possibility for the lesion to be malignant. b) Malignant tumors in Carney’s complex can arise from any organ, which in the index case presented with multiple tumors over many years culminating in an ovarian malignant tumor, whereas the sister developed a thyroid malignanc...