Correlation of Erythrocyte Distribution Width Values with Preeclampsia and Preeclampsia with Severity Criteria

Aim: To determine the correlation of the red cell distribution width values with pre-eclampsia and pre-eclampsia with severity criteria. Materials and methods: Cross-sectional, prospective study of patients who met the inclusion criteria in the period from August 2019 to August 2020. Statistical analysis was performed using Student's t test and Spearman's correlation to calculate the dependence between the non-parametric variables, the value of p<0.05 was considered statistically significant. Results: 9 patients with pre-eclampsia and 30 pre-eclampsia were obtained with severity criteria. There was no statistical difference when comparing the RDW of patients with pre-eclampsia and pre-eclampsia with severity criteria (p=0.226), in patients with systolic blood pressure values ≥160mmHg there was an increase in RDW levels (p=0.042) Objective: To determine the correlation of erythrocyte distribution width values with pre-eclampsia and pre-eclampsia with severity criteria. Conclusions: There is a significant relationship between increased RDW and systolic blood pressure values ≥160mmHg.

Preeclampsia is a multisystemic disorder characterized by hypertension and proteinuria, which occur for the first time after 20 weeks of gestation, it is one of the main causes of maternal morbidity and mortality and perinatal worldwide.1 Hypertensive disorders of pregnancy affect approximately 15% of pregnancies and represent 18% of maternal deaths in the world, in Mexico according to the Ministry of Health, the Preeclampsia accounts for up to 34% of all maternal deaths.2 Although it is characterized by alteration in the remodeling of the spiral arteries whose origin is an alteration in the invasion of the extravillous trophoblast, conditioning placental hypoperfusion that generates reactive oxygen species and cytokines pro-inflammatory,3 in such a way that chronic hypoperfusion of the maternal-fetal circulation could compromise the erythrocytes, this whose main function is the transport of oxygen, for which the erythrocyte distribution width (RDW) describes the percentage variation in the size of the erythrocytes, Values between 11% and 15% are generally considered normal. A value above this range indicates a heterogeneous population of erythrocytes, that is, increased RDW values are related to when there is excessive destruction of red blood cells or a deficit in its production.

https://www.stephypublishers.com/cicmr/pdf/CICMR.MS.ID.000516.pdf 


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