Palate Obturators in the Phono-Articular System in Defects Caused by Nasal T / NK Cell Lymphoma | Stephy Publishers
Internal and Emergency Medicine | Stephy Publishers
Abstract:
Lymphomas are frequent malignant
neoplasms, due to the destructive and rapidity of their clinical course, they
present extensive areas of necrosis, which could be induced by the Epstein Bar
virus (EBV) that is present in most of these lymphomas causing oro-nasal
communications that they have an impact on phonation, chewing, swallowing and
loss of self-esteem. Due to the extension of this type of communication, they
represent a challenge in surgical rehabilitation opting for a prosthetic
device.
Introduction
Lymphomas are a group of neoplasms originating in the
immune system, whose cells are widely distributed and have an extensive
functional range. In the head and neck region there is a high incidence of
nasal type T / NK cell lymphomas associated with the Epstein Var virus (EBV)
showing a similar pattern of strain type distribution between neoplastic
tissues and reactive processes. EBV may infect cells of the T / NK lineage,
raising the possibility of exposure of the nasal, nasopharyngeal, hard and soft
palate mucosa. It is also argued that EBV may participate in the induction of
cytokines, in particular tumor necrosis, factor kappa-β and metalloproteases in
virally infected cells, causing areas of necrosis.1 The oral cavity, the nasal
cavity, the maxillary sinuses and the rest of the oropharynx area is
constituted by the presence of the hard palate that structurally forms a
physical barrier and the soft palate that together with a series of movements
of the pharyngeal walls achieves the separation and coupling of the nasal space
with the oral and pharyngeal space. The anatomical integrity of both is
important to ensure proper function. Maxillary defects can be restored by means
of a prosthetic device designed to close these acquired communications. A
palatal obturator is defined as a prosthetic device designed
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