Stephy Publishers

  SOJ Diabetes and Endocrinology Care - (SOJDEC) |  Stephy Publishers Abstract Aim:  Type 2 diabetes mellitus (T2DM) is the most common metabolic disorder and its pathogenesis is characterized by a combination of peripheral insulin resistance and impaired insulin secretary capacity of pancreatic β cell. Over the years, there has been increasing deaths from T2DM. In Myanmar, there is little information on its causes, due to few published data on the prevalence of MS and its association with T2DM. This study aims at identifying the metabolic risk markers leading to MS in T2DM, as well as the impact of MS on the insulin resistance. Methods:  Hundred T2DM patients were recruited from Diabetic Clinic, Yangon General Hospital. The clinical evaluation consisted of waist circumference, blood pressure, height and weight measurements; the biochemical analysis included determination of fasting plasma glucose, serum insulin and fasting lipid profile. Plasma glucose level was...

  SOJ Diabetes and Endocrinology Care - (SOJDEC) | Stephy Publishers Abstract Globally more than 550 women die per year from childbirth-related causes. Around 9% of women suffer from postpartum post-traumatic stress disorder after childbirth. Postpartum bipolar disorder is humor episodes such as mania, hypomania or depression, which start throughout pregnancy or in few weeks after child bearing. Fifty percent (50%) worldwide estimation of motherly deaths arise in sub-Saharan Africa region alone. Depression is a devastating temperament and mental sickness touching around 13% of postpartum mothers worldwide. The occurrence of 25%-60% of depression is typical of low- and middle-income countries. A combined prevalence of 14.4% of teenage deliveries was revealed in Cameroon where there is unsatisfactory information on the risk factors of motherly mortality and mother care after childbirth. In hinterland local therapists especially in Bororo and Pygmies communities, have developed indige...

  Abstract Purpose: To evaluate the influence of nadir prostate-specific antigen (PSA) level and time to PSA nadir following androgen deprivation therapy (ADT)on disease progression of castration-resistant prostate cancer (CRPC) in patients with metastatic, hormone-sensitive prostate cancer (mHSPC). Patients and methods: A total of 90 patients with metastatic, hormone-sensitive prostate cancer treated with androgen deprivation therapy in our hospital were included in our retrospective study. Patients’ characteristics, PSA at PADT initiation (initial PSA), PSA nadir, TTN, follow up time, CRPC event were analyzed using Kaplan-Meier analysis and Cox regression model. Results: At a median follow-up of 12 months, 57 patients (63.3%) showed disease progression of CRPC Both PSA nadir and time to PSA nadir (TTN) was independent and significant predictors of CRPC event. Patients with higher PSA nadir (≥0.2ng/dL) and shorter time to PSA nadir (TTN <6 months) had significant shorter time t...

  SOJ Pediatrics and Clinical Neonatology  - (SOJPCN)|  Stephy Publishers Abstract Background:  Postoperative outcome in children is multifactorial. Among the reported predictors of postoperative outcome, preoperative anemia has been related to adverse outcome in children. A secondary analysis was undertaken to determine the correlation between hemoglobin levels and postoperative outcome in children included in a cohort of an observational pediatric study published previously since this analysis has not been done. Objective:  To determine the correlation between preoperative, intra-operative, postoperative hemoglobin levels and postoperative outcome in children in neurosurgery, abdominal and orthopedic surgery. Methods:  Secondary analysis of a sub-cohort of 252 pediatric surgical patients with a median age of 62 months [12.50-144.00]. Results:  Preoperative hemoglobin levels were negatively correlated to length of stay in the intensive care unit (LOSI...